Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 17/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565083 | 0.88 | RAB9A (0.47) | MEN1THRBRAB9AKMT2ASLC2A1 | |
| SCHEMBL7570193 | 0.87 | RAB9A (0.47) | MEN1THRBRAB9AKMT2ASLC2A1 | |
| SCHEMBL7561719 | 0.84 | RAB9A (0.44) | MEN1THRBRAB9AKMT2ASLC2A1 | |
| SCHEMBL7570012 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7590623 | 0.79 | RAB9A (0.54) | MEN1THRBRAB9AKMT2ASLC2A1 | |
| SCHEMBL7563837 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7789068 | 0.75 | PTGS2 (0.74) | PTGS2PTGS1ALOX5 | |
| SCHEMBL12124929 | 0.73 | RAB9A (0.69) | MEN1THRBRAB9AKMT2ASLC2A1 | |
| SCHEMBL7796089 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6671775 | 0.73 | PTGS2 (0.71) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093838-A | FOR TREATING SKIN-RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, ECZEMA | ALLERGAN SALES, INC. (US) | 2000-07-25 | — | — | US | disclosed |