SCHEMBL7789196

SCHEMBL7789196

CCc1ccc(C=NN=Cc2ccc(C)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
NPC1 O15118 5/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAOA P21397 1/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 3/20 0.37
PKM P14618 2/20 0.37
BLM P54132 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPK1 P28482 1/20 0.37
THPO P40225 1/20 0.37
CHRM5 P08912 1/20 0.37
GRM5 P41594 1/20 0.37
PMP22 Q01453 1/20 0.37
CASP3 P42574 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789193 1.00 ALOX5 (0.41) ALOX5PTGS1PTGS2NPC1RAB9A
SCHEMBL7788571 0.88 GRIN2D (0.41) PTGS1PTGS2NPC1RAB9ASMN1; SMN2
SCHEMBL7788574 0.88 GRIN2D (0.41) PTGS1PTGS2NPC1RAB9ASMN1; SMN2
SCHEMBL7793232 0.87 PLA2G7 (0.42) ALOX5PTGS1PTGS2NPC1RAB9A
SCHEMBL7793238 0.87 PLA2G7 (0.42) ALOX5PTGS1PTGS2NPC1RAB9A
SCHEMBL7788427 0.85 NPC1 (0.42) ALOX5PTGS1PTGS2NPC1RAB9A
SCHEMBL7788428 0.85 NPC1 (0.42) ALOX5PTGS1PTGS2NPC1RAB9A
SCHEMBL7789254 0.85 GRIN2D (0.52) NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4
SCHEMBL7789256 0.85 GRIN2D (0.52) NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4
SCHEMBL7793418 0.84 NPC1 (0.40) ALOX5PTGS1PTGS2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed