Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789631 | 1.00 | CTSK (0.55) | CTSKNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL24095771 | 0.80 | NPC1 (0.54) | CTSKNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL6758408 | 0.78 | TDP1 (0.55) | CTSKNPC1RAB9ATDP1TSHR | |
| SCHEMBL6758410 | 0.78 | TDP1 (0.55) | CTSKNPC1RAB9ATDP1TSHR | |
| SCHEMBL1920841 | 0.78 | TDP1 (0.54) | CTSKNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL7454113 | 0.78 | CTSK (0.53) | CTSKNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL31482407 | 0.78 | SMN1; SMN2 (0.54) | CTSKNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3930322 | 0.77 | TDP1 (0.58) | CTSKNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL2301673 | 0.77 | EPHX2 (0.50) | RECQLTDP1LMNAKMT2ACYP1A2 | |
| SCHEMBL7966733 | 0.77 | CA12 (0.47) | CTSKGPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748801-B1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEM (JP) | 2001-12-19 | — | — | EP | disclosed |
| EP-0527385-A1 | Alpha-trifluoromethyl substituted, saturated bicyclic amines and process for their preparation | BAYER AG (DE) | 1993-02-17 | — | — | EP | disclosed |