Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848391 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL9848476 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL844472 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL14040614 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL9273434 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL8121337 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL4385673 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL27648565 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL3630691 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL29833659 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAPOLBALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748801-B1 | 2-ISOXAZOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING RELATED DERIVATIVES FROM THE SAME | DAICEL CHEM (JP) | 2001-12-19 | — | — | EP | disclosed |
| EP-0527385-A1 | Alpha-trifluoromethyl substituted, saturated bicyclic amines and process for their preparation | BAYER AG (DE) | 1993-02-17 | — | — | EP | disclosed |