SCHEMBL7789636

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7502720	0.88	PTGS2 (0.54)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL7501561	0.88	PTGS2 (0.54)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL8138706	0.87	PTGS2 (0.53)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL7796653	0.84	CA1 (0.54)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL8152990	0.84	CA2 (0.54)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL8145237	0.82	PTGS2 (0.51)	PTGS2PTGS1CA2CA1KIF11
	SCHEMBL7799127	0.80	PTGS2 (0.76)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL8152668	0.80	PTGS1 (0.52)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL8146656	0.80	PTGS1 (0.51)	PTGS2PTGS1CA12CA2CA9
	SCHEMBL213239	0.77	PTGS2 (0.56)	PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.