Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793669 | 0.84 | FOLH1 (0.49) | FOLH1GSTK1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7784238 | 0.84 | FOLH1 (0.49) | FOLH1GSTK1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7784233 | 0.82 | FOLH1 (0.46) | FOLH1GSTK1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7792757 | 0.81 | FOLH1 (0.49) | FOLH1GSTK1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7789656 | 0.81 | FOLH1 (0.45) | FOLH1GSTK1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7794220 | 0.79 | FOLH1 (0.43) | FOLH1GSTK1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7789658 | 0.79 | FOLH1 (0.43) | FOLH1FFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL7793707 | 0.78 | TSHR (0.39) | FOLH1ALDH1A1LMNATSHR | |
| SCHEMBL7793694 | 0.76 | ALDH1A1 (0.41) | FOLH1FFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL8002202 | 0.71 | FFAR4 (0.65) | FFAR4FFAR1ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |