Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784253 | 0.86 | TSHR (0.39) | TSHRFOLH1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7784245 | 0.83 | TSHR (0.39) | TSHRFOLH1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7789659 | 0.78 | FOLH1 (0.49) | TSHRFOLH1LMNAALDH1A1 | |
| SCHEMBL7793709 | 0.72 | L3MBTL1 (0.40) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 | |
| SCHEMBL7790033 | 0.72 | FOLH1 (0.34) | FOLH1GAAKMT2A | |
| SCHEMBL7793680 | 0.72 | LMNA (0.43) | FOLH1LMNAALDH1A1GAA | |
| SCHEMBL22813743 | 0.72 | TSHR (0.61) | TSHRL3MBTL1LMNAALDH1A1GLA | |
| SCHEMBL16281094 | 0.70 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1GLA | |
| SCHEMBL4010658 | 0.70 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1GLA | |
| SCHEMBL8104827 | 0.70 | TSHR (0.48) | TSHRL3MBTL1LMNAALDH1A1SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |