Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.66 |
| ▸ | RARG | P13631 | 15/20 | 0.66 |
| ▸ | RARA | P10276 | 13/20 | 0.66 |
| ▸ | RXRA | P19793 | 5/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679095 | 0.97 | RARG (0.71) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL5846367 | 0.88 | RARG (0.52) | RARBRARGRARARXRA | |
| SCHEMBL5846356 | 0.88 | RARG (0.61) | RARBRARGRARARXRA | |
| SCHEMBL7784235 | 0.88 | RARB (0.61) | RARBRARGRARARXRAABCB1 | |
| SCHEMBL7790069 | 0.87 | RARG (0.67) | RARBRARGRARARXRARXRB | |
| SCHEMBL497952 | 0.85 | RARG (0.56) | RARBRARGRARARXRA | |
| SCHEMBL8345661 | 0.84 | RARG (0.60) | RARBRARGRARARXRARXRB | |
| SCHEMBL5845591 | 0.83 | RARG (0.93) | RARBRARGRARARXRARXRB | |
| SCHEMBL7790045 | 0.83 | RARG (0.56) | RARBRARGRARARXRAHNF4A | |
| SCHEMBL10040343 | 0.82 | RARG (0.51) | RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |