Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.67 |
| ▸ | RARB | P10826 | 14/20 | 0.67 |
| ▸ | RXRA | P19793 | 7/20 | 0.67 |
| ▸ | RARA | P10276 | 12/20 | 0.54 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 3/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847370 | 0.90 | RARG (0.53) | RARGRARBRXRARARARXRB | |
| SCHEMBL3679095 | 0.88 | RARG (0.71) | RARGRARBRXRARARA | |
| SCHEMBL7789667 | 0.87 | RARB (0.66) | RARGRARBRXRARARARXRB | |
| SCHEMBL7790045 | 0.86 | RARG (0.56) | RARGRARBRXRARARA | |
| SCHEMBL5846356 | 0.79 | RARG (0.61) | RARGRARBRXRARARA | |
| SCHEMBL497952 | 0.79 | RARG (0.56) | RARGRARBRXRARARA | |
| SCHEMBL7784235 | 0.79 | RARB (0.61) | RARGRARBRXRARARARXRB | |
| SCHEMBL5847730 | 0.79 | RARG (0.46) | RARGRARBRXRARARA | |
| SCHEMBL7790097 | 0.78 | RARG (0.83) | RARGRARBRXRARARARXRB | |
| SCHEMBL5846367 | 0.78 | RARG (0.52) | RARGRARBRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |