Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.56 |
| ▸ | RARB | P10826 | 10/20 | 0.56 |
| ▸ | RARA | P10276 | 9/20 | 0.56 |
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847730 | 0.91 | RARG (0.46) | RARGRARBRARARXRAEGFR | |
| SCHEMBL7790069 | 0.86 | RARG (0.67) | RARGRARBRARARXRA | |
| SCHEMBL3679095 | 0.84 | RARG (0.71) | RARGRARBRARARXRA | |
| SCHEMBL7784249 | 0.84 | RARG (0.62) | RARGRARBRARARXRAEGFR | |
| SCHEMBL7789667 | 0.83 | RARB (0.66) | RARGRARBRARARXRAHNF4A | |
| SCHEMBL2918656 | 0.82 | EGFR (0.67) | RARGRARBRARARXRAEGFR | |
| SCHEMBL5846380 | 0.78 | RARG (0.78) | RARGRARBRARARXRA | |
| SCHEMBL5847370 | 0.78 | RARG (0.53) | RARGRARBRARARXRA | |
| SCHEMBL5846356 | 0.77 | RARG (0.61) | RARGRARBRARARXRA | |
| SCHEMBL497952 | 0.75 | RARG (0.56) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952974-B1 | BIPHENYL DERIVATIVES SUBSTITUTED BY AN AROMATIC OR HETEROAROMATIC RADICAL AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | disclosed |