Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 8/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791341 | 0.87 | CAPN1 (0.61) | CAPN1KCNA5CTSB | |
| SCHEMBL7782223 | 0.83 | MEN1 (0.47) | MEN1KMT2AKCNA5KDM4EMAPT | |
| SCHEMBL7789847 | 0.82 | PPARG (0.39) | CTSSCAPN1 | |
| SCHEMBL7787794 | 0.76 | CAPN1 (0.53) | MEN1KMT2ACAPN1CTSBL3MBTL1 | |
| SCHEMBL7782210 | 0.75 | DYRK1A (0.47) | CAPN1KCNA5CTSB | |
| SCHEMBL7790034 | 0.74 | CAPN1 (0.48) | MEN1KMT2ACAPN1MAPTHTT | |
| SCHEMBL7787775 | 0.74 | CAPN1 (0.51) | CAPN1CTSB | |
| SCHEMBL7787789 | 0.74 | CAPN1 (0.48) | CAPN1CTSB | |
| SCHEMBL7787026 | 0.72 | CAPN1 (0.51) | CAPN1CTSB | |
| SCHEMBL7459754 | 0.71 | CAPN1 (0.54) | MEN1KMT2ACAPN1CTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |