Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782229 | 0.88 | CAPN1 (0.51) | CAPN1 | |
| SCHEMBL7789876 | 0.85 | DYRK1A (0.46) | PPARG | |
| SCHEMBL7789802 | 0.82 | MEN1 (0.46) | CTSSCAPN1 | |
| SCHEMBL7782141 | 0.77 | HPGDS (0.47) | — | |
| SCHEMBL7787026 | 0.77 | CAPN1 (0.51) | CAPN1 | |
| SCHEMBL7787789 | 0.76 | CAPN1 (0.48) | CAPN1 | |
| SCHEMBL7325294 | 0.75 | KMO (0.49) | — | |
| SCHEMBL7787775 | 0.74 | CAPN1 (0.51) | CAPN1 | |
| SCHEMBL7787794 | 0.72 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL7377479 | 0.71 | NPC1 (0.47) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |