⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789599 | 0.87 | LMNA (0.31) | — | |
| SCHEMBL6867256 | 0.86 | HSP90AB1 (0.38) | — | |
| SCHEMBL6867247 | 0.86 | HSP90AB1 (0.38) | — | |
| SCHEMBL7793405 | 0.83 | LMNA (0.30) | — | |
| SCHEMBL7792732 | 0.82 | LMNA (0.30) | — | |
| SCHEMBL7792709 | 0.80 | POLB (0.30) | — | |
| SCHEMBL7784152 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL6860302 | 0.72 | HSP90AB1 (0.45) | — | |
| SCHEMBL6860305 | 0.72 | HSP90AB1 (0.45) | — | |
| SCHEMBL6943889 | 0.72 | HSP90AB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |