Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793405 | 0.90 | LMNA (0.30) | LMNA | |
| SCHEMBL7605642 | 0.86 | ALDH1A1 (0.34) | LMNA | |
| SCHEMBL6867048 | 0.85 | LMNA (0.41) | LMNA | |
| SCHEMBL6867046 | 0.85 | LMNA (0.41) | LMNA | |
| SCHEMBL7789936 | 0.82 | — | — | |
| SCHEMBL7792709 | 0.82 | POLB (0.30) | — | |
| SCHEMBL7612818 | 0.76 | ALDH1A1 (0.43) | LMNA | |
| SCHEMBL6864422 | 0.75 | HSP90AB1 (0.42) | LMNA | |
| SCHEMBL6864423 | 0.75 | HSP90AB1 (0.42) | LMNA | |
| SCHEMBL7784152 | 0.75 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |