SCHEMBL7789974

SCHEMBL7789974

Cc1ccc2[c]ccc(C)c2c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.43
CYP2A6 P11509 3/20 0.43
ALDH1A1 P00352 5/20 0.34
TDP1 Q9NUW8 4/20 0.34
TP53 P04637 2/20 0.34
KDM4E B2RXH2 4/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
ALOX15 P16050 2/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 3/20 0.32
GAA P10253 2/20 0.32
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPA1 O75762 1/20 0.31
ACHE P22303 2/20 0.31
RXFP1 Q9HBX9 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18317277 0.74 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1TDP1KDM4E
SCHEMBL2250860 0.73 CYP1A2 (0.39) CYP1A2CYP2A6ALDH1A1TDP1TP53
SCHEMBL67474 0.71 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1KDM4EHPGD
SCHEMBL5011557 0.71 CYP1A2 (0.34) CYP1A2CYP2A6MAPT
SCHEMBL6601643 0.71 CYP1A2 (0.38) CYP1A2CYP2A6ALDH1A1TDP1TP53
SCHEMBL28957262 0.70 POLB (0.40) CYP2A6ALDH1A1TP53LMNAGAA
SCHEMBL667960 0.70 CYP1A2 (0.45) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL69340 0.70 CYP2A6 (0.41) CYP1A2CYP2A6ALDH1A1TDP1KDM4E
SCHEMBL18317667 0.69 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1TDP1KDM4E
SCHEMBL29845621 0.67 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed
US-4259330-A Nematocidal phosphoramidates ROHM AND HAAS COMPANY (US) 1981-03-31 US disclosed
US-4139614-A FOR HUMAN AND VETERINARY MEDICINE ROHM AND HAAS COMPANY (US) 1979-02-13 US disclosed