Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292398 | 0.76 | CYP1A2 (0.40) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7789974 | 0.71 | CYP1A2 (0.43) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL667256 | 0.67 | CYP1A2 (0.52) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11026596 | 0.66 | CYP2A6 (0.43) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4304565 | 0.65 | CYP1A2 (0.44) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL593462 | 0.64 | CYP2A6 (0.48) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6399521 | 0.64 | RAPGEF4 (0.33) | KDM4E | |
| SCHEMBL8840917 | 0.61 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3873030 | 0.61 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL819377 | 0.61 | CYP2A6 (0.50) | CYP1A2CYP2A6ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923569-B1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0923569-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006711-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |