Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 1.00 |
| ▸ | DNM1 | Q05193 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 4/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | TLR4 | O00206 | 3/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.65 |
| ▸ | HTR2C | P28335 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.65 |
| ▸ | HTR2B | P41595 | 4/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | HTR6 | P50406 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carazolol SCHEMBL6511163 | 1.00 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL29354289 | 1.00 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL77903 | 1.00 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL10568418 | 0.99 | ADRB2 (0.98) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL7530148 | 0.99 | ADRB2 (0.98) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| SCHEMBL2992432 | 0.89 | ADRB2 (0.79) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Fluorocarazolol SCHEMBL14155316 | 0.89 | ADRB2 (0.79) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| SCHEMBL3002063 | 0.88 | ADRB2 (0.78) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| SCHEMBL13495721 | 0.86 | ADRB2 (0.76) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| SCHEMBL12407602 | 0.85 | ADRB2 (0.74) | ADRB2DNM1HTR1ADRD3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4016 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250360149-A1 | GPCR INHIBITORS AND USES THEREOF | GPCR THERAPEUTICS INC (KR) | 2025-11-27 | — | — | US | claimed |
| EP-4536239-A1 | GPCR INHIBITORS AND USES THEREOF | GPCR Therapeutics, Inc. (KR) | 2025-04-16 | — | — | EP | claimed |
| WO-2025050038-A2 | GPCR INHIBITORS AND USES THEREOF | GPCR THERAPEUTICS, INC. (KR) | 2025-03-06 | — | — | WO | claimed |
| CN-119233997-A | Tetrahedral antibodies | 生物分子控股有限责任公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4463485-A2 | TETRAHEDRAL ANTIBODIES | Biomolecular Holdings LLC (US) | 2024-11-20 | — | — | EP | claimed |
| US-20240301022-A1 | GLYCOPROTEINS HAVING LIPID MOBILIZING PROPERTIES AND THERAPEUTIC USES THEREOF | UNIV ASTON (GB) | 2024-09-12 | — | — | US | claimed |
| CN-118384290-A | Hybrid immunoglobulins containing non-peptide linkages | 生物分子控股有限责任公司 | 2024-07-26 | — | — | CN | claimed |
| WO-2024102699-A1 | GUANYLATE CYCLASE (GC) STIMULATOR FORMULATIONS AND USES THEREOF | ELANCO US, Inc. (US) | 2024-05-16 | — | — | WO | claimed |
| WO-2023239937-A1 | GPCR INHIBITORS AND USES THEREOF | GPCR THERAPEUTICS, INC. (KR) | 2023-12-14 | — | — | WO | claimed |
| WO-2023183932-A2 | MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | claimed |
| US-4782043-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1988-11-01 | — | — | US | claimed |
| EP-0278158-A2 | Renin inhibitors containing phenylalanyl-histidine replacements | MERCK & CO. INC. (US) | 1988-08-17 | — | — | EP | claimed |
| EP-0273696-A2 | Renin inhibitors containing histidine replacements | MERCK & CO. INC. (US) | 1988-07-06 | — | — | EP | claimed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |
| EP-0163237-A2 | Di- and tri-peptidal renin inhibitors | MERCK & CO. INC. (US) | 1985-12-04 | — | — | EP | claimed |
| EP-0157409-A2 | Renin inhibitors containing 2-substituted statine | MERCK & CO. INC. (US) | 1985-10-09 | — | — | EP | claimed |
| EP-0156318-A2 | C-terminal amide cyclic renin inhibitors containing peptide isosteres | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | claimed |
| EP-0156322-A2 | Renin inhibitors containing peptide isosteres | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | claimed |
| EP-0129189-A2 | Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | claimed |
| US-4445735-A | Electrical connection device for high density contacts | COMPAGNIE INTERNATIONALE POUR L'INFORMATIQUE CII-HONEYWELL BULL (SOCIETE ANONYME) (FR) | 1984-05-01 | — | — | US | claimed |