Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.74 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.74 |
| ▸ | HTR1A | P08908 | 6/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.53 |
| ▸ | HTR2C | P28335 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | HTR2B | P41595 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495721 | 0.88 | ADRB2 (0.76) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| SCHEMBL12407602 | 0.87 | ADRB2 (0.74) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL77903 | 0.85 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL29354289 | 0.85 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL6511163 | 0.85 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL77901 | 0.85 | ADRB2 (1.00) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL7530148 | 0.84 | ADRB2 (0.98) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Carazolol SCHEMBL10568418 | 0.84 | ADRB2 (0.98) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| SCHEMBL11088812 | 0.77 | ADRB2 (0.72) | ADRB2DNM1HTR1ADRD3ADRA2A | |
| Fluorocarazolol SCHEMBL14155316 | 0.77 | ADRB2 (0.79) | ADRB2DNM1HTR1ADRD3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935852-B2 | Fluoridation method | GE HEALTHCARE LIMITED (GB) | 2011-05-03 | — | — | US | disclosed |
| US-7642373-B2 | Forming for example [18F]-dopamine or [18F]-uracil via reaction of iodonium salt precursor, where use of free radical scavenger improves yield of aryl fluoride | GE HEALTHCARE LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-20070092441-A1 | Fluoridation method | GE HEALTHCARE LIMITED (GB) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092441-A1 | Fluoridation method | FLNB, FLNA, ARFGEF1 | ADRB2 2670/4885DNM1 595/4885HTR1A 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.