Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | BCHE | P06276 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501701 | 0.77 | SIGMAR1 (0.43) | SIGMAR1KDM1AMAOB | |
| SCHEMBL2150153 | 0.74 | SIGMAR1 (0.45) | SIGMAR1KDM1AMAOBESR1ESR2 | |
| SCHEMBL11800619 | 0.74 | KDM1A (0.44) | SIGMAR1KDM1AMAOBLMNA | |
| Phenol SCHEMBL9774501 | 0.73 | ESR2 (0.40) | SIGMAR1KDM1AMAOBESR1ESR2 | |
| SCHEMBL7782464 | 0.72 | ESR2 (0.48) | SIGMAR1KDM1AMAOBESR1ESR2 | |
| SCHEMBL31230954 | 0.71 | KDM1A (0.44) | SIGMAR1KDM1AMAOB | |
| SCHEMBL29556714 | 0.70 | KDM1A (0.44) | SIGMAR1KDM1AMAOB | |
| SCHEMBL7787282 | 0.70 | KDM1A (0.48) | SIGMAR1KDM1AMAOB | |
| SCHEMBL8734058 | 0.70 | KDM1A (0.44) | SIGMAR1KDM1AMAOB | |
| Ammonia Solution, Strong SCHEMBL27550700 | 0.70 | ESR2 (0.47) | SIGMAR1KDM1AMAOBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |
| WO-2001051527-A1 | PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |