Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359725 | 0.82 | TDP1 (0.58) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5933377 | 0.82 | TDP1 (0.66) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7796988 | 0.78 | L3MBTL1 (0.47) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7228409 | 0.78 | MEN1 (0.61) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2315734 | 0.77 | RCE1 (0.52) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4731326 | 0.75 | TDP1 (0.58) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2479873 | 0.75 | LMNA (0.59) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4467147 | 0.73 | RCE1 (0.52) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1901574 | 0.73 | RCE1 (0.52) | TDP1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7076078 | 0.73 | HDAC1 (0.64) | TDP1NPC1RAB9AALOX5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |