Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 5/20 | 0.55 |
| ▸ | AMPD3 | Q01432 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | CDA | P32320 | 1/20 | 0.41 |
| ▸ | CD99 | P14209 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371414 | 1.00 | ADA (0.55) | ADAAMPD3ADORA3ADORA1ADORA2A | |
| Coformycin SCHEMBL13697497 | 0.90 | ADA (0.68) | ADAAMPD3ADORA3ADORA1ALDH1A1 | |
| Coformycin SCHEMBL442534 | 0.90 | ADA (0.68) | ADAAMPD3ADORA3ADORA1ALDH1A1 | |
| Coformycin SCHEMBL8373037 | 0.90 | ADA (0.68) | ADAAMPD3ADORA3ADORA1ALDH1A1 | |
| Coformycin SCHEMBL7796895 | 0.90 | ADA (0.68) | ADAAMPD3ADORA3ADORA1ALDH1A1 | |
| Coformycin SCHEMBL13697294 | 0.90 | ADA (0.68) | ADAAMPD3ADORA3ADORA1ALDH1A1 | |
| SCHEMBL10705678 | 0.87 | ADA (0.55) | ADAAMPD3ADORA3ADORA1ADORA2A | |
| SCHEMBL10792647 | 0.87 | ADA (0.55) | ADAAMPD3ADORA3ADORA1ADORA2A | |
| SCHEMBL13111762 | 0.80 | ADA (0.58) | ADAAMPD3ADORA3ADORA1ALDH1A1 | |
| SCHEMBL8518998 | 0.80 | CDA (0.43) | ADAAMPD3ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261666-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYOCARDIAL DYSFUNCTION ASSOCIATED WITH SIRS OR SEPSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261666-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MYOCARDIAL DYSFUNCTION ASSOCIATED WITH SIRS OR SEPSIS | ADA, XDH, PNP | ADA 1/4885AMPD3 20/4885ADORA3 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.