Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 8/20 | 0.41 |
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201066 | 0.85 | CCR5 (0.45) | CCR5TACR2TACR1HRH1TACR3 | |
| Hydrochloric Acid SCHEMBL6493645 | 0.85 | CCR5 (0.45) | CCR5TACR2TACR1HRH1TACR3 | |
| SCHEMBL5199609 | 0.83 | TACR2 (0.43) | CCR5TACR2TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL6492132 | 0.82 | TACR2 (0.42) | CCR5TACR2TACR1TACR3 | |
| SCHEMBL6500864 | 0.80 | EPHX2 (0.45) | CCR5 | |
| SCHEMBL5200156 | 0.77 | CCR5 (0.52) | CCR5TACR2TACR1TACR3 | |
| SCHEMBL5201160 | 0.76 | CCR5 (0.52) | CCR5TACR2TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL6490210 | 0.76 | CCR5 (0.52) | CCR5TACR2TACR1TACR3 | |
| SCHEMBL5203851 | 0.75 | HSD11B1 (0.39) | CCR5 | |
| SCHEMBL5200054 | 0.75 | CCR5 (0.51) | CCR5TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150970-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Sanofi-Aventis (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047572-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2000-08-17 | — | — | WO | disclosed |