Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21251603 | 0.93 | CASP2 (0.54) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19578063 | 0.91 | CASP2 (0.57) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL22838207 | 0.91 | CASP2 (0.57) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL24507280 | 0.91 | CASP2 (0.57) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL15677521 | 0.91 | CASP2 (0.57) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL24982530 | 0.91 | CASP2 (0.57) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL19988365 | 0.90 | EPHX1 (0.43) | CASP2EPHX1ACHEMMP2HTT | |
| SCHEMBL24238536 | 0.90 | EPHX1 (0.43) | CASP2EPHX1ACHEMMP2HTT | |
| SCHEMBL22447142 | 0.86 | EPHX1 (0.50) | CASP2EPHX1ZDHHC20ZDHHC2NAAA | |
| SCHEMBL21076334 | 0.86 | EPHX1 (0.50) | CASP2EPHX1ZDHHC20ZDHHC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414238-B1 | SUBSTITUTED IMIDAZOLYL-CARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-03-24 | — | — | EP | disclosed |
| EP-3722283-A1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2020-10-14 | — | — | EP | disclosed |
| WO-2010150840-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2010-12-29 | — | — | WO | disclosed |