Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789986 | 1.00 | TOP2A (0.61) | TOP2ATOP2BKDM4EL3MBTL1MALT1 | |
| SCHEMBL7790417 | 0.95 | TOP2A (0.65) | TOP2ATOP2BKDM4EL3MBTL1MALT1 | |
| SCHEMBL7794455 | 0.95 | TOP2A (0.66) | TOP2ATOP2BKDM4EL3MBTL1MALT1 | |
| SCHEMBL7794020 | 0.95 | TOP2A (0.66) | TOP2ATOP2BKDM4EL3MBTL1MALT1 | |
| SCHEMBL7794477 | 0.93 | TOP2A (0.51) | TOP2ATOP2BKDM4EL3MBTL1MALT1 | |
| SCHEMBL7790450 | 0.87 | TOP2A (0.71) | TOP2ATOP2BKDM4ETDP1MAPT | |
| SCHEMBL7790425 | 0.87 | TOP2A (0.71) | TOP2ATOP2BKDM4ETDP1MAPT | |
| SCHEMBL7790550 | 0.87 | TOP2A (0.71) | TOP2ATOP2BKDM4ETDP1MAPT | |
| SCHEMBL7790428 | 0.83 | TOP2A (0.73) | TOP2ATOP2BKDM4ERPS6KA3TDP1 | |
| SCHEMBL7789896 | 0.83 | TOP2A (0.73) | TOP2ATOP2BKDM4ERPS6KA3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156056-A1 | 5-GLYCOSYLOXY-6-HYDROXYNAPHTHO 2,3-f]QUINOLINE-7,12-DIONE HAVING ANTICANCER ACTIVITIES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-11-21 | — | — | EP | disclosed |