Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367026 | 0.92 | DRD3 (0.53) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7800051 | 0.92 | DRD3 (0.52) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7330880 | 0.90 | ADRA1D (0.56) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7799044 | 0.90 | ADRA1D (0.60) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7330882 | 0.90 | ADRA1D (0.56) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7799046 | 0.90 | ADRA1D (0.60) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL7368019 | 0.90 | DRD3 (0.55) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| Bromide SCHEMBL7333859 | 0.89 | ADRA1D (0.59) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| Bromide SCHEMBL7799003 | 0.89 | ADRA1D (0.59) | DRD3ADRA1DADRA1AADRA1BDRD2 | |
| Bromide SCHEMBL7333855 | 0.89 | ADRA1D (0.59) | DRD3ADRA1DADRA1AADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781126-B1 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON SPA (IT) | 2001-12-12 | — | — | EP | disclosed |