Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735869 | 0.85 | POLB (0.58) | POLBKDM4EALDH1A1LMNAALOX5 | |
| Caffeic Acid SCHEMBL27469970 | 0.75 | KDM4E (0.69) | AKR1C3AKR1C2POLBKDM4EHSD17B10 | |
| Caffeic Acid SCHEMBL7790618 | 0.74 | KDM4E (0.56) | CCR5POLBKDM4EHSD17B10MMP1 | |
| 4-Methoxycinnamic Acid SCHEMBL10634478 | 0.71 | THRB (0.83) | KDM4ETHRBMEN1HDAC3ALDH1A1 | |
| Caffeic Acid SCHEMBL28575890 | 0.71 | KDM4E (0.86) | AKR1C3AKR1C2POLBKDM4EHSD17B10 | |
| SCHEMBL4266183 | 0.71 | APP (0.49) | AKR1C3AKR1C2POLBKDM4EHSD17B10 | |
| SCHEMBL4266198 | 0.71 | APP (0.49) | AKR1C3AKR1C2POLBKDM4EHSD17B10 | |
| SCHEMBL31716606 | 0.71 | APP (0.49) | AKR1C3AKR1C2POLBKDM4EHSD17B10 | |
| SCHEMBL20914985 | 0.69 | APP (0.77) | AKR1C3AKR1C2KDM4EHSD17B10CA12 | |
| SCHEMBL30925683 | 0.69 | APP (0.75) | CCR5POLBMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150956-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047561-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2000-08-17 | — | — | WO | disclosed |