Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3735872 | 0.87 | LDHA (0.59) | KDM4EMAPTTDP1HSD17B10POLB | |
| SCHEMBL30925684 | 0.79 | MMP1 (0.60) | MMP1MMP2MMP9CA2PTPN1 | |
| Caffeic Acid SCHEMBL28575890 | 0.76 | KDM4E (0.86) | KDM4EMMP1MAPTTDP1HSD17B10 | |
| SCHEMBL10436394 | 0.76 | LDHA (0.76) | POLBCYP1A2KMT2A | |
| Rosmarinic Acid SCHEMBL22362628 | 0.76 | TDP1 (0.93) | KDM4EMMP1MAPTTDP1HSD17B10 | |
| Caffeic Acid SCHEMBL27469970 | 0.73 | KDM4E (0.69) | KDM4EMMP1MAPTTDP1HSD17B10 | |
| Tyrosine SCHEMBL25429180 | 0.73 | KDM4E (0.60) | KDM4EMMP1MAPTTDP1HSD17B10 | |
| SCHEMBL16382871 | 0.73 | MMP1 (0.70) | KDM4EMMP1THRBAPPMMP2 | |
| Tyrosine SCHEMBL25429176 | 0.73 | KDM4E (0.60) | KDM4EMMP1MAPTTDP1HSD17B10 | |
| Caffeic Acid SCHEMBL7064846 | 0.73 | KDM4E (1.00) | KDM4EMMP1MAPTTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150956-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047561-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2000-08-17 | — | — | WO | disclosed |