Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741284 | 0.97 | CTSL (0.47) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL3727056 | 0.92 | CTSL (0.52) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL13077457 | 0.87 | CTSL (0.47) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL3732115 | 0.87 | ATM (0.55) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL3740504 | 0.83 | CTSL (0.48) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL7791893 | 0.83 | CTSL (0.45) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL3732674 | 0.82 | CTSL (0.58) | CTSLCTSBCTSKCTSSELANE | |
| SCHEMBL3738798 | 0.82 | CTSL (0.47) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL11969990 | 0.80 | CTSB (0.58) | CASP1CTSLCTSBCTSKCTSS | |
| SCHEMBL22685495 | 0.80 | CTSB (0.58) | CASP1CTSLCTSBCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150956-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047561-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2000-08-17 | — | — | WO | disclosed |