Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386254 | 0.83 | HTR2A (0.36) | AHRHTR2CHTR2AHTR2BPNMT | |
| SCHEMBL7795105 | 0.74 | PNMT (0.34) | PNMTADRA2AADRA2BADRA2CMETAP1 | |
| SCHEMBL207730 | 0.65 | AHR (0.39) | AHRHTR2CSMN1; SMN2 | |
| SCHEMBL8343541 | 0.65 | TRPA1 (0.34) | TSHR | |
| SCHEMBL20528826 | 0.65 | TRPA1 (0.34) | TSHR | |
| SCHEMBL9413877 | 0.64 | — | — | |
| SCHEMBL1896564 | 0.62 | HTR2C (0.38) | AHRHTR2CHTR2AHTR2BPNMT | |
| SCHEMBL31513977 | 0.62 | HTR2C (0.38) | AHRHTR2CHTR2AHTR2BPNMT | |
| SCHEMBL2580002 | 0.62 | HTR2C (0.42) | AHRHTR2CHTR2AHTR2BPNMT | |
| Hydrochloric Acid SCHEMBL28666905 | 0.62 | AHR (0.38) | AHRHTR2CHTR2AHTR2BPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155698-A1 | ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES | Nitto Kasei Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |