Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.52 |
| ▸ | FABP3 | P05413 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587149 | 0.81 | IDO1 (0.58) | SMN1; SMN2TP53 | |
| SCHEMBL7020135 | 0.81 | IDO1 (0.58) | SMN1; SMN2TP53 | |
| SCHEMBL7071110 | 0.76 | FOLH1 (0.66) | MRGPRX4TSHRSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL28855166 | 0.75 | NR4A2 (0.55) | MRGPRX4FABP3FABP4FABP5TSHR | |
| SCHEMBL5839484 | 0.75 | FABP3 (0.78) | MRGPRX4FABP3FABP4FABP5ALDH1A1 | |
| SCHEMBL8864622 | 0.73 | SMN1; SMN2 (0.69) | MRGPRX4TSHRCASP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29579676 | 0.73 | PDPK1 (0.68) | MRGPRX4SMN1; SMN2PDPK1HPGDLMNA | |
| SCHEMBL658196 | 0.73 | PDPK1 (0.68) | MRGPRX4SMN1; SMN2PDPK1HPGDLMNA | |
| Phthalic Acid SCHEMBL21802423 | 0.73 | NR4A1 (0.76) | TSHRCASP1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL586345 | 0.73 | PDPK1 (0.59) | PDPK1HPGDALDH1A1PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763513-B1 | Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide | NIHON NOHYAKU CO LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-1026135-A1 | Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide | Nihon Nohyaku Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5981807-A | REACTING A HALO-SUBSTITUTED PHENYLETHANOL WITH PHTHALIC ANHYDRIDE, PERFORMING OPTICAL RESOLUTION ON THE RESULTING COMPOUND USING AN OPTICALLY ACTIVE ORGANIC AMINE AS A RESOLVING AGENT, PERFORMING HYDROLYSIS OR ALCOHOLYSIS | NIHON NOHYAKU CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5756862-A | RACEMIZATION WITH ACID CATALYST | NIHON NOHYAKU CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |