Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.49 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119542 | 0.89 | ALDH1A1 (0.50) | NR4A2TSHRCASP1SMN1; SMN2NR4A1 | |
| SCHEMBL28056097 | 0.84 | ALDH1A1 (0.49) | NR4A2TSHRNR4A1MRGPRX4SRD5A2 | |
| SCHEMBL23040963 | 0.81 | RXRA (0.51) | NR4A2SMN1; SMN2MRGPRX4ALDH1A1HPGD | |
| SCHEMBL27857639 | 0.80 | NPC1 (0.49) | NR4A2TSHRSMN1; SMN2TP53 | |
| SCHEMBL27792967 | 0.76 | KDM4E (0.46) | TSHRALDH1A1TP53 | |
| SCHEMBL6307118 | 0.76 | HDAC1 (0.57) | NR4A2TSHRCASP1SMN1; SMN2NR4A1 | |
| SCHEMBL6066505 | 0.76 | HDAC8 (0.56) | NR4A2NR4A1NR4A3MRGPRX4TTR | |
| SCHEMBL27383637 | 0.76 | TSHR (0.51) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL27794541 | 0.76 | KDM4E (0.42) | NR4A2TSHRTP53 | |
| SCHEMBL11621292 | 0.75 | IDO1 (0.65) | SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812898-B | The method for treating metabolic syndrome by adjusting the β of heat shock protein (HSP) 90 | 博格有限责任公司 | 2018-01-30 | — | — | CN | disclosed |