SCHEMBL7790691

SCHEMBL7790691

C=Cc1ccc2c(c1)C=[C]C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR7 P34969 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794550 0.85 ALDH1A1 (0.37) ALDH1A1TP53TDP1TRPA1
SCHEMBL387117 0.69 ADRA2A (0.35)
SCHEMBL7641543 0.67 ALDH1A1 (0.39) ALDH1A1TP53TDP1TRPA1
SCHEMBL1697578 0.66 ALDH1A1 (0.48) ALDH1A1TP53TDP1TRPA1
SCHEMBL29475832 0.66 ALDH1A1 (0.48) ALDH1A1TP53TDP1TRPA1
SCHEMBL31122823 0.66 ALDH1A1 (0.48) ALDH1A1TP53TDP1TRPA1
SCHEMBL30786494 0.66
SCHEMBL3297666 0.64 ALDH1A1 (0.46) ALDH1A1TP53TDP1TRPA1
SCHEMBL2867311 0.64 ALDH1A1 (0.46) ALDH1A1TP53TDP1TRPA1
SCHEMBL1882235 0.63 ALDH1A1 (0.50) ALDH1A1TP53TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed