Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123767 | 0.91 | THRB (0.54) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL28459735 | 0.88 | THRB (0.51) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL7644509 | 0.85 | THRB (0.58) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL14123765 | 0.84 | THRB (0.48) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL9174872 | 0.84 | THRB (0.57) | THRBALDH1A1TSHRTP53HIF1A | |
| Hydrochloric Acid SCHEMBL30094529 | 0.84 | THRB (0.57) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL14123725 | 0.83 | THRB (0.47) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL14123772 | 0.81 | THRB (0.45) | THRBALDH1A1TSHRTP53HIF1A | |
| SCHEMBL14123775 | 0.80 | ALDH1A1 (0.54) | THRBALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL600753 | 0.79 | THRB (0.51) | THRBALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849258-B1 | Process for the preparation of ethylenically unsaturated isocyanates | NOVARTIS AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| EP-0730615-B1 | LOW-ODOUR ADHESIVE COMPOSITION COMPRISING URETHANE GROUP CONTAINING (METH)ACRYLATE | HENKEL KGAA (DE) | 2000-09-06 | — | — | EP | disclosed |
| US-5990345-A | Process for preparation of ethylenically unsaturated isocyanates | NOVARTIS AG (CH) | 1999-11-23 | — | — | US | disclosed |
| EP-0849258-A1 | Process for the preparation of ethylenically unsaturated isocyanates | Novartis AG (CH) | 1998-06-24 | — | — | EP | disclosed |
| US-5700891-A | CONTAINS ACTIVATOR SYSTEM FOR FREE-RADICAL POLYMERIZATION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-12-23 | — | — | US | disclosed |
| EP-0730615-A1 | LOW-ODOUR ADHESIVE COMPOSITION COMPRISING URETHANE GROUP CONTAINING (METH)ACRYLATE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014725-A1 | LOW-ODOUR ADHESIVE COMPOSITION COMPRISING URETHANE GROUP CONTAINING (METH)ACRYLATE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-06-01 | — | — | WO | disclosed |