SCHEMBL7790826

SCHEMBL7790826

CCC(CN1CCCCC1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HTT P42858 2/20 0.46
MITF O75030 1/20 0.46
RAB9A P51151 1/20 0.46
GFER P55789 1/20 0.46
PAX8 Q06710 1/20 0.46
ATM Q13315 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
POLB P06746 1/20 0.46
CYP2D6 P10635 4/20 0.44
CYP3A4 P08684 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
KCNA5 P22460 2/20 0.44
KCNH2 Q12809 2/20 0.44
KCNE1 P15382 1/20 0.44
TSHR P16473 2/20 0.44
HIF1A Q16665 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11927945 0.98 ALDH1A1 (0.47) ALDH1A1HTTMITFRAB9AGFER
SCHEMBL16509775 0.84 GAA (0.63) ALDH1A1GFERPOLBCYP2D6KCNH2
SCHEMBL7155342 0.83 MEN1 (0.55) ALDH1A1CYP2D6CYP3A4CYP2C19CYP1A2
SCHEMBL8744393 0.83 CYP1A2 (0.45) ALDH1A1RAB9AATMCYP2D6CYP3A4
SCHEMBL13572993 0.83 SIGMAR1 (0.49) KCNH2GAAMEN1KMT2A
SCHEMBL12513625 0.83 POLB (0.51) ALDH1A1PAX8ATMSMN1; SMN2POLB
SCHEMBL13039127 0.81 ALDH1A1 (0.50) ALDH1A1HTTMITFRAB9AGFER
SCHEMBL13039121 0.81 ALDH1A1 (0.43) ALDH1A1HTTMITFRAB9AGFER
SCHEMBL13039128 0.81 ALDH1A1 (0.50) ALDH1A1HTTMITFRAB9AGFER
SCHEMBL13039130 0.81 ALDH1A1 (0.43) ALDH1A1HTTMITFRAB9AGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2474527-A1 IONIC LIQUID CONTAINING ALLYLSULFONATE ANION Wako Pure Chemical Industries, Ltd. (JP) 2012-07-11 EP disclosed
US-20010047097-A1 Process for the preparation of arylethylamines by amination of arylolefins AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 2001-11-29 US disclosed
EP-1157983-A1 Process for the preparation of arylethylamines via the amination of arylolefins Aventis Research & Technologies GmbH & Co KG (DE) 2001-11-28 EP disclosed