Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.66 |
| ▸ | CCR5 | P51681 | 3/20 | 0.66 |
| ▸ | CCR8 | P51685 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | CBFB | Q13951 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terpyridine SCHEMBL7785028 | 0.86 | KDM4E (0.60) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL1617719 | 0.83 | CCR1 (0.96) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL517337 | 0.81 | CCR1 (1.00) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7790887 | 0.80 | CCR1 (0.40) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7785067 | 0.80 | CBFB (0.47) | CCR1CCR5CCR8KDM4ELMNA | |
| 2-Mercaptobenzimidazole SCHEMBL7794586 | 0.80 | CCR1 (0.60) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL9876002 | 0.75 | LMNA (0.44) | CCR1CCR5CCR8KDM4ELMNA | |
| 2-Mercaptoethanol SCHEMBL7790768 | 0.75 | CCR1 (0.72) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL7552182 | 0.73 | CCR1 (0.82) | CCR1CCR5CCR8KDM4ELMNA | |
| Mercaptopurine Anhydrous SCHEMBL7795114 | 0.73 | CCR1 (0.55) | CCR1CCR5CCR8KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155025-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050431-A1 | PLATINUM (II) COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2000-08-31 | — | — | WO | disclosed |