SCHEMBL7790897

SCHEMBL7790897

FC(F)(F)c1ccccc1P

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
IDO1 P14902 2/20 0.40
TSHR P16473 1/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.39
HSD11B1 P28845 1/20 0.38
NFKB1 P19838 1/20 0.38
KIF11 P52732 1/20 0.38
HTR2C P28335 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CA2 P00918 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468876 0.91 ALDH1A1 (0.38) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL6286508 0.79 ALDH1A1 (0.31) ALDH1A1TDP1POLBL3MBTL1TSHR
SCHEMBL63469 0.78 ALDH1A1 (0.52) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL29441997 0.78 ALDH1A1 (0.52) ALDH1A1TDP1POLBL3MBTL1IDO1
Hydrogen Sulfide SCHEMBL28274662 0.76 ALDH1A1 (0.50) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL15656859 0.75 PDK2 (0.42) ALDH1A1TDP1HSD11B1CYP1A2CYP3A4
SCHEMBL24727995 0.75 TAS2R14 (0.40) ALDH1A1TDP1POLBL3MBTL1HSD11B1
SCHEMBL8030449 0.74
Bromide SCHEMBL29093546 0.73 ALDH1A1 (0.48) ALDH1A1TDP1POLBL3MBTL1IDO1
Iodide SCHEMBL29093541 0.73 ALDH1A1 (0.48) ALDH1A1TDP1POLBL3MBTL1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP claimed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO claimed
CN-115066465-A Composition, heat conduction material, heat conduction sheet and device with heat conduction layer 富士胶片株式会社 2022-09-16 CN disclosed
EP-3728391-A1 METHOD FOR THE POLYMERISATION OF CYCLOOLEFINS BY MEANS OF RING-OPENING METATHESIS Demeta (FR) 2020-10-28 EP disclosed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP disclosed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO disclosed