Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797293 | 0.99 | NPSR1 (0.55) | NPSR1TSHRALDH1A1THRBHTT | |
| SCHEMBL7797332 | 0.99 | NPSR1 (0.55) | NPSR1TSHRALDH1A1THRBHTT | |
| SCHEMBL7799311 | 0.97 | NPSR1 (0.56) | NPSR1TSHRALDH1A1THRBHTT | |
| SCHEMBL6559851 | 0.94 | NPSR1 (0.58) | NPSR1TSHRALDH1A1THRBHTT | |
| SCHEMBL18315198 | 0.92 | NPSR1 (0.51) | NPSR1TSHRALDH1A1POLBL3MBTL1 | |
| SCHEMBL10150634 | 0.92 | NPSR1 (0.48) | NPSR1TSHRALDH1A1THRBHTT | |
| SCHEMBL18315199 | 0.89 | NPSR1 (0.51) | NPSR1TSHRALDH1A1POLBL3MBTL1 | |
| SCHEMBL18315201 | 0.86 | NPSR1 (0.53) | NPSR1TSHRALDH1A1THRBPOLB | |
| SCHEMBL10150638 | 0.86 | NPSR1 (0.50) | NPSR1TSHRALDH1A1THRBHTT | |
| SCHEMBL11299461 | 0.85 | ALDH1A1 (0.48) | NPSR1TSHRALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |