Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489891 | 0.95 | THRB (0.50) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 | |
| SCHEMBL6559851 | 0.91 | NPSR1 (0.58) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 | |
| SCHEMBL6559249 | 0.87 | NPSR1 (0.47) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 | |
| SCHEMBL10150638 | 0.86 | NPSR1 (0.50) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 | |
| SCHEMBL18315201 | 0.86 | NPSR1 (0.53) | ALDH1A1NPSR1THRBLMNATSHR | |
| SCHEMBL7799311 | 0.85 | NPSR1 (0.56) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 | |
| SCHEMBL7791073 | 0.85 | NPSR1 (0.56) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 | |
| SCHEMBL1322672 | 0.84 | PRKCA (0.44) | ALDH1A1NPSR1CYP17A1CYP19A1MEN1 | |
| SCHEMBL12132675 | 0.84 | ALDH1A1 (0.58) | ALDH1A1NPSR1CYP17A1CYP19A1MEN1 | |
| SCHEMBL10171133 | 0.84 | ALDH1A1 (0.37) | ALDH1A1NPSR1THRBCYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960419-B | (methyl) acrylate compounds and its manufacture method | 三菱瓦斯化学株式会社 | 2018-03-16 | — | — | CN | disclosed |
| EP-0032905-A4 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS. | FOLEY WILLIAM M JUN | 1981-08-27 | — | — | EP | disclosed |
| EP-0032905-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY, Jr., William M. (US) | 1981-08-05 | — | — | EP | disclosed |
| WO-1980002840-A1 | CONTACT LENSES WITH POLYMER BOUND ASEPTICIZING AGENTS | FOLEY W | 1980-12-24 | — | — | WO | disclosed |