Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881325 | 0.75 | HDAC3 (0.44) | KMT2APRNPRXFP1POLBSLC22A12 | |
| SCHEMBL4421777 | 0.73 | MAPT (0.42) | PRNPRXFP1SLC22A12KDRPRKD3 | |
| SCHEMBL28757760 | 0.72 | RAC1 (0.38) | KMT2APRNPRXFP1POLBMAPT | |
| SCHEMBL7786986 | 0.69 | KCNK2 (0.44) | TAS1R3TAS1R1KMT2APRNPRXFP1 | |
| SCHEMBL4591807 | 0.67 | RAC1 (0.52) | KMT2APRNPRXFP1POLBSLC22A12 | |
| SCHEMBL20683281 | 0.66 | RAC1 (0.54) | KMT2APRNPRXFP1POLBSLC22A12 | |
| SCHEMBL27619323 | 0.66 | DAO (0.39) | KDRPRKD3MAP4K4GSK3AGSK3B | |
| SCHEMBL4419754 | 0.66 | DAO (0.39) | KDRPRKD3MAP4K4GSK3AGSK3B | |
| SCHEMBL25403102 | 0.64 | RAC1 (0.52) | KMT2APRNPRXFP1POLBSLC22A12 | |
| SCHEMBL27619372 | 0.64 | RAC1 (0.41) | CYP3A4KMT2APRNPRXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |