Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789879 | 0.87 | CAPN1 (0.48) | KCNK2PRNPRAB9ARXFP1MAPT | |
| SCHEMBL7789875 | 0.87 | CAPN1 (0.48) | KCNK2PRNPRAB9ARXFP1MAPT | |
| SCHEMBL27676562 | 0.75 | HDAC3 (0.53) | KMT2AMEN1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL11189080 | 0.75 | RXFP1 (0.60) | KCNK2PRNPKMT2AMEN1RAB9A | |
| SCHEMBL27656629 | 0.74 | RAB9A (0.54) | KMT2AMEN1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL1064818 | 0.72 | HDAC1 (0.67) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL7787801 | 0.69 | CAPN1 (0.58) | KMT2AMEN1KDM4E | |
| SCHEMBL7787804 | 0.69 | CAPN1 (0.58) | KMT2AMEN1KDM4E | |
| SCHEMBL7791371 | 0.69 | TAS1R3 (0.38) | PRNPKMT2AMEN1RXFP1MAPT | |
| SCHEMBL29177611 | 0.69 | RXFP1 (0.60) | PRNPKMT2AMEN1RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |