Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.66 |
| ▸ | XIAP | P98170 | 11/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785927 | 0.94 | GHSR (0.65) | GHSRXIAPAGTR1NPY1RFPR1 | |
| SCHEMBL7791643 | 0.94 | GHSR (0.68) | GHSRXIAPAGTR1NPY1RCYP11B1 | |
| SCHEMBL7791735 | 0.93 | GHSR (0.69) | GHSRXIAPAGTR1NPY1RFPR1 | |
| SCHEMBL7791581 | 0.93 | GHSR (0.67) | GHSRXIAPAGTR1CYP11B1CYP11B2 | |
| SCHEMBL7794419 | 0.92 | GHSR (0.58) | GHSRXIAPAGTR1CYP11B1CYP11B2 | |
| SCHEMBL7795596 | 0.91 | GHSR (0.81) | GHSRXIAPAGTR1NPY1RFPR1 | |
| SCHEMBL7791588 | 0.91 | GHSR (0.67) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7786019 | 0.89 | GHSR (0.80) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7791728 | 0.89 | GHSR (0.66) | GHSRXIAPAGTR1NPY1RFPR1 | |
| SCHEMBL8328786 | 0.88 | GHSR (0.69) | GHSRXIAPAGTR1NPY1RFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | claimed |