Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.67 |
| ▸ | XIAP | P98170 | 6/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 5/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791973 | 0.94 | GHSR (0.69) | GHSRXIAPAGTR1AVPR2NPY1R | |
| SCHEMBL7794445 | 0.91 | GHSR (0.62) | GHSRXIAPAGTR1NPY1RPTGER1 | |
| SCHEMBL7795975 | 0.91 | GHSR (0.71) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785880 | 0.90 | GHSR (0.73) | GHSRXIAPAGTR1NPY1RPTGER1 | |
| SCHEMBL8330701 | 0.89 | GHSR (0.67) | GHSRXIAPAGTR1AVPR2NPY1R | |
| SCHEMBL7794451 | 0.88 | GHSR (0.81) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL8328518 | 0.87 | GHSR (0.66) | GHSRXIAPAGTR1AVPR2NPY1R | |
| SCHEMBL7785886 | 0.87 | GHSR (0.73) | GHSRXIAPAGTR1NPY1RPTGER1 | |
| SCHEMBL7785844 | 0.87 | GHSR (0.80) | GHSRXIAPAGTR1NPY1RPTGER1 | |
| SCHEMBL7786019 | 0.87 | GHSR (0.80) | GHSRXIAPAGTR1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |