SCHEMBL7791871

SCHEMBL7791871

C=CCc1ccc(C=NN=Cc2ccc(OC)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
TSHR P16473 2/20 0.73
CYP3A4 P08684 2/20 0.73
TP53 P04637 2/20 0.73
ALOX15 P16050 1/20 0.73
ALOX12 P18054 1/20 0.73
GRIN2D O15399 2/20 0.50
GRIN3B O60391 2/20 0.50
GRIN1 Q05586 2/20 0.50
GRIN2A Q12879 2/20 0.50
GRIN2B Q13224 2/20 0.50
GRIN2C Q14957 2/20 0.50
GRIN3A Q8TCU5 2/20 0.50
PPARG P37231 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
G6PC1 P35575 1/20 0.44
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791869 1.00 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
SCHEMBL10946799 0.86 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
Estragole SCHEMBL900647 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
Estragole SCHEMBL57204 0.86 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
SCHEMBL7791826 0.86 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
SCHEMBL7791828 0.86 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
SCHEMBL7793237 0.84 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
SCHEMBL7793231 0.84 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
Estragole SCHEMBL29777399 0.84 ALDH1A1 (0.96) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53
SCHEMBL11776228 0.82 GRIN2D (0.68) ALDH1A1SMN1; SMN2TSHRCYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed