Estragole

Estragole

SCHEMBL900647

C=CCc1ccc(OC)cc1.C=CCc1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
CYP3A4 P08684 2/20 1.00
TP53 P04637 1/20 1.00
ALOX15 P16050 1/20 1.00
TSHR P16473 1/20 1.00
ALOX12 P18054 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
PPARG P37231 1/20 0.57
PPARD Q03181 1/20 0.57
PPARA Q07869 1/20 0.57
IDO1 P14902 4/20 0.52
PTGS1 P23219 2/20 0.52
ALOX5 P09917 1/20 0.52
AR P10275 1/20 0.52
TRPM8 Q7Z2W7 1/20 0.52
FFAR4 Q5NUL3 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Estragole SCHEMBL57204 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4TP53ALOX15TSHR
Estragole SCHEMBL29777399 0.98 ALDH1A1 (0.96) ALDH1A1CYP3A4TP53ALOX15TSHR
SCHEMBL10910253 0.94 ALDH1A1 (0.88) ALDH1A1CYP3A4TP53ALOX15TSHR
SCHEMBL8576732 0.94 ALDH1A1 (0.88) ALDH1A1CYP3A4TP53ALOX15TSHR
SCHEMBL11228368 0.94 ALDH1A1 (0.88) ALDH1A1CYP3A4TP53ALOX15TSHR
Estragole SCHEMBL4256218 0.89 ALDH1A1 (0.79) ALDH1A1CYP3A4TP53ALOX15TSHR
SCHEMBL9797652 0.89 SMN1; SMN2 (0.79) ALDH1A1CYP3A4TP53ALOX15TSHR
SCHEMBL7791871 0.86 ALDH1A1 (0.73) ALDH1A1CYP3A4TP53ALOX15TSHR
SCHEMBL8576729 0.86 ALDH1A1 (0.73) ALDH1A1CYP3A4TP53ALOX15TSHR
Estragole SCHEMBL29145860 0.86 ALDH1A1 (0.73) ALDH1A1CYP3A4TP53ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013131498-A2 ANTI-MICROBIAL COMPONENT AND USING OF THE SAME TOMAS BATA UNIVERSITY IN ZLIN (CZ) 2013-09-12 WO disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed
US-6121234-A ORALLY COADMINISTERING TO MAMMAL PHARMACEUTICAL COMPOUND AND ESSENTIAL OIL AVMAX, INC. (US) 2000-09-19 US disclosed
US-5716928-A ADMINISTERING DRUG CONCURRENTLY WITH ESSENTIAL OIL AVMAX, INC. (US) 1998-02-10 US disclosed
US-5665386-A Use of essential oils to increase bioavailability of oral pharmaceutical compounds AVMAX, INC. (US) 1997-09-09 US disclosed
CN-1100630-A Breast plumping bath lotion and perfumed soap DISHENG NEW TECH RESEARCH INST (CN) 1995-03-29 CN disclosed