Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11606266 | 0.91 | KCNA3 (0.61) | HTR7KCNA3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8517442 | 0.87 | KCNA3 (0.54) | HTR7KCNA3ALDH1A1KDM4E | |
| SCHEMBL7791786 | 0.85 | KCNA3 (0.50) | KCNA3ALDH1A1KDM4EHTR1BTERT | |
| SCHEMBL11604034 | 0.85 | KCNA3 (0.65) | HTR7KCNA3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9539542 | 0.84 | ALDH1A1 (0.54) | HTR7KCNA3ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11604535 | 0.84 | KCNA3 (0.63) | HTR7KCNA3ALDH1A1KDM4EHTR1B | |
| SCHEMBL7786384 | 0.82 | MAPT (0.52) | HTR7KCNA3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7792612 | 0.82 | KCNA3 (0.51) | HTR7KCNA3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8380843 | 0.81 | TTR (0.49) | KCNA3ALDH1A1KDM4EHTR1BTERT | |
| SCHEMBL7795728 | 0.81 | KCNA3 (0.52) | KCNA3ALDH1A1KDM4EHTR1BTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |