Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Proline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL10141185 | 1.00 | — | — | |
| Proline SCHEMBL718906 | 1.00 | BLM (0.52) | — | |
| Proline SCHEMBL458825 | 1.00 | BLM (0.52) | — | |
| Proline SCHEMBL18875607 | 1.00 | — | — | |
| Proline SCHEMBL146827 | 1.00 | BLM (0.52) | — | |
| Proline SCHEMBL10141181 | 1.00 | — | — | |
| Proline SCHEMBL6894672 | 1.00 | BLM (0.52) | — | |
| Proline SCHEMBL6894675 | 1.00 | BLM (0.52) | — | |
| D-Proline SCHEMBL21462052 | 1.00 | BLM (0.52) | — | |
| Proline SCHEMBL13248912 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 553922 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118345003-A | Application of proline in improving acid resistance of lactic acid bacteria | 青岛东海药业有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118345056-A | Space-separated orthogonal translation system and application thereof | 江苏集萃未来食品技术研究所有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118344873-A | Silicon nitride etching solution for inhibiting tip oxide regeneration, preparation method and application | 浙江奥首材料科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118340884-A | Pharmaceutical composition for efficiently eradicating helicobacter pylori, and preparation method and application thereof | 江苏安泰生物技术有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118318681-A | Identification method for drought resistance of corn variety | 吉林农业科技学院 | 2024-07-12 | — | — | CN | claimed |
| CN-118324599-A | Amino acid racemization method based on anionic water-soluble macromolecule grafted racemization catalyst | 山东理工大学 | 2024-07-12 | — | — | CN | claimed |
| CN-118338895-A | Novel dialysate | 甘布罗伦迪亚股份公司 | 2024-07-12 | — | — | CN | claimed |
| US-20240226010-A9 | METHOD FOR THE PRODUCTION OF PRECISELY SIZED MACRO- AND MICRO-ELP CONTAINING PARTICLES FOR THE DELIVERY OF THERAPEUTIC AGENTS | UNIVERSITY OF MISSISSIPPI MEDICAL CENTER | 2024-07-11 | — | — | US | claimed |
| US-20240226323-A9 | GOLD CLUSTERS, COMPOSITIONS, AND METHODS FOR TREATMENT OF DEPRESSION | SHENZHEN PROFOUND VIEW PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2024-07-11 | — | — | US | claimed |
| US-20240229297-A1 | ANTIBODY LIBRARIES WITH MAXIMIZED ANTIBODY DEVELOPABILITY CHARACTERISTICS | RULES-BASED MEDICINE INC. (US) | 2024-07-11 | — | — | US | claimed |
| US-3971736-A | HEXA- AND HEPTA-PEPTIDES, ANTIINFLAMMATORY, ANTIULCER, ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | claimed |
| US-3959248-A | TRIPEPTIDES; ANTIDEPRESSANTS | MERCK & CO., INC. (US) | 1976-05-25 | — | — | US | claimed |
| US-3954975-A | Salts of ACTH-peptides and processes for their manufacture | CIBA-GEIGY CORPORATION (US) | 1976-05-04 | — | — | US | claimed |
| US-3953416-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same | FOLKERS KARL | 1976-04-27 | — | — | US | claimed |
| US-3950513-A | NONTOXIC AMINO ACID | NOVO TERAPEUTISK LABORATORIUM A/S (DK) | 1976-04-13 | — | — | US | claimed |
| US-3947589-A | Fungicidal methods employing amino acid derivatives | RIKAGAKU KENKYUSHO (JA) | 1976-03-30 | — | — | US | claimed |
| US-3943038-A | Method for producing amino acids by culturing hydrogen-oxidizing bacteria | AJINOMOTO CO., INC. (JA) | 1976-03-09 | — | — | US | claimed |
| US-3936469-A | Process for preparing N-carboxylic anhydrides of amino acids | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | claimed |
| US-3933783-A | Formation of peptide bonds in the presence of isonitriles | AJINOMOTO CO., INC. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3933813-A | Process for the production of mercaptoethyl containing compounds | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-01-20 | — | — | US | claimed |