Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSPO | P30536 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE6D | O43924 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786251 | 0.82 | ALDH1A1 (0.62) | L3MBTL1KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL4780057 | 0.81 | CYP2C19 (0.60) | L3MBTL1CYP2C19CYP2C9CYP1A2KDM4E | |
| SCHEMBL7795665 | 0.80 | NPSR1 (0.56) | L3MBTL1CYP2C19CYP2C9CYP1A2POLB | |
| SCHEMBL7792121 | 0.80 | IDO1 (0.47) | L3MBTL1KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL7796432 | 0.79 | HDAC6 (0.46) | KDM4EPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7786325 | 0.79 | HDAC6 (0.46) | KDM4EPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8402493 | 0.79 | ALDH1A1 (0.56) | L3MBTL1KDM4EPOLBLMNATSPO | |
| SCHEMBL4784826 | 0.78 | CYP2C19 (0.57) | L3MBTL1CYP2C19CYP2C9CYP1A2KDM4E | |
| SCHEMBL4784820 | 0.78 | CYP2C19 (0.57) | L3MBTL1CYP2C19CYP2C9CYP1A2KDM4E | |
| SCHEMBL7794772 | 0.76 | CYP1A2 (0.45) | L3MBTL1CYP1A2KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |