Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786325 | 1.00 | HDAC6 (0.46) | HDAC6SMN1; SMN2RECQLLMNAHTT | |
| SCHEMBL7786251 | 0.84 | ALDH1A1 (0.62) | SMN1; SMN2RECQLLMNAHTTALDH1A1 | |
| SCHEMBL7794772 | 0.83 | CYP1A2 (0.45) | SMN1; SMN2RECQLLMNAHTTALDH1A1 | |
| SCHEMBL7795665 | 0.82 | NPSR1 (0.56) | SMN1; SMN2RECQLLMNAHTTALDH1A1 | |
| SCHEMBL7792693 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2RECQLLMNAHTTALDH1A1 | |
| SCHEMBL7792081 | 0.81 | PTGDR2 (0.43) | SMN1; SMN2RECQLALDH1A1KDM4EPTGDR2 | |
| SCHEMBL7796343 | 0.81 | PTGDR2 (0.43) | SMN1; SMN2RECQLALDH1A1KDM4EPTGDR2 | |
| SCHEMBL7792344 | 0.81 | PTGDR2 (0.43) | SMN1; SMN2RECQLALDH1A1KDM4EPTGDR2 | |
| SCHEMBL8402493 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2RECQLLMNAALDH1A1KDM4E | |
| SCHEMBL7796129 | 0.80 | CYP1A2 (0.43) | SMN1; SMN2RECQLALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |