Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786160 | 0.99 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRL3MBTL1HTT | |
| SCHEMBL7794869 | 0.97 | KDM4E (0.46) | ALDH1A1KDM4ETSHRL3MBTL1HTT | |
| SCHEMBL7795919 | 0.97 | KDM4E (0.48) | ALDH1A1KDM4ETSHRL3MBTL1HTT | |
| SCHEMBL7795838 | 0.97 | HRH3 (0.46) | ALDH1A1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL7786120 | 0.97 | HRH3 (0.46) | ALDH1A1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL7792673 | 0.96 | KDM4E (0.46) | ALDH1A1KDM4ETSHRL3MBTL1HTT | |
| SCHEMBL7792327 | 0.96 | KDM4E (0.47) | ALDH1A1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL7791841 | 0.96 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRL3MBTL1HTT | |
| SCHEMBL7792019 | 0.96 | KDM4E (0.47) | ALDH1A1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL7794725 | 0.95 | KDM4E (0.48) | ALDH1A1KDM4ETSHRL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |