Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 8/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.34 |
| ▸ | TUBB | P07437 | 5/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789099 | 0.94 | KDR (0.39) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7517663 | 0.89 | MAPK1 (0.41) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7792153 | 0.88 | MAPK1 (0.39) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| Hydrochloric Acid SCHEMBL7792147 | 0.88 | MAPK1 (0.40) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7789092 | 0.85 | MAPK1 (0.39) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7793945 | 0.81 | KDR (0.38) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7793948 | 0.75 | KDR (0.38) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7793917 | 0.72 | CSNK2A1 (0.59) | — | |
| SCHEMBL7792996 | 0.71 | CSNK2A2 (0.41) | KDRMAPK1ADORA3PTGS1RXFP1 | |
| SCHEMBL7792227 | 0.71 | LMNA (0.36) | KDRMAPK1ADORA3PTGS1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010047021-A1 | Cancer treatment | THE PROCTER & GAMBLE COMPANY | 2001-11-29 | — | — | US | disclosed |
| WO-2001083457-A2 | BENZIMIDAZOLE-2-CARBAMATES AND THEIR USE IN CANCER TREATMENT | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047021-A1 | Cancer treatment | MUSK, ALK, BCOR | KDR 3354/4885MAPK1 4166/4885ADORA3 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.